ASFNR clinical state-of-practice: For posterior circulation large vessel occlusion stroke, use noncontrast CT to exclude hemorrhage, CT angiography to identify occlusion, and MRI with DWI as reference standard. Imaging scores like PC-ASPECTS help select patients for thrombectomy.
The ACR Appropriateness Criteria 2026 update provides imaging guidelines for suspected or confirmed diffuse lung disease, covering initial evaluation, acute exacerbation, and surveillance.
New expert consensus framework for symptomatic B3 breast lesions: assess concordance, lower excision threshold for discordant/palpable lesions, conservative management for concordant non-atypical lesions, and risk-based surveillance for atypia.
ACR Appropriateness Criteria for indolent lung cancer: For patients with slow-growing subsolid nodules or atypical cysts where surveillance is chosen over intervention, imaging follow-up aims to detect changes that alter management, with modality selection guided by accuracy and…
Personalizing PSMA radiopharmaceutical selection may enhance prostate cancer theranostics by matching agent properties to patient and tumor characteristics, according to an AJR review.
AJR review clarifies why distinguishing one- and two-sided hypothesis tests is essential for interpreting radiology research: two-sided tests are default; one-sided tests require prespecified directional hypotheses. Misuse inflates false-positive rates.
Consensus-driven guidance for oncologic FDG PET in diabetics: point-of-care glucose, permissive thresholds, avoid correctional insulin, continue insulin pumps in basal mode. SGLT-2 inhibitors and GLP-1 agonists have limited evidence. Prospective studies needed.
This special article in the American Journal of Roentgenology (AJR) identifies bullying, gossip, and incivility as ongoing issues in radiology workplaces and provides a framework for navigating office politics. It outlines practical strategies for individuals and leaders to reco…
An AJR editorial examines how authors disclose use of generative AI technologies when submitting manuscripts, highlighting current practices and the need for clear policies (no quantitative data reported in source).
A deep learning CT deblurring algorithm increased coronary artery calcium detectability from 39% to 48% at high dose and achieved 39% detectability at routine dose (6% improvement over standard reconstruction) in a phantom study.
Protocol for a prospective 50-patient study aiming to build a machine learning model that predicts MR elastography-derived kidney stiffness directly from routine CT attenuation values, potentially obviating dedicated elastography.
A YOLO-based deep learning model with wavelet attention achieved AUC 0.94–0.99 for classifying pediatric femoral neck fractures on internal testing. On external testing, 31 orthopedic surgeons’ accuracy improved to 79–87% with model assistance (P<0.001).
A multi-window deep learning system detected six acute abdominal emergencies on CT with macro AUROC 0.941 internally and 0.879 externally, but external F1 was 0.545 (0.648 after recalibration); the retrospective study requires prospective multisite validation.
Eine Meta-Analyse von 16 Studien zeigt, dass Radiomics-Modelle genetische Mutationen bei kolorektalem Karzinom mit einer gepoolten Sensitivität von 0.75 und Spezifität von 0.78 (AUC 0.79) vorhersagen können. Die Integration klinischer Daten verbesserte die Sensitivität, jedoch w…
CT-based AI body composition model classified urinary stone composition with AUC 0.90 (95% CI 0.78–0.98) and identified 75% of future incident stones (specificity 89%) in a retrospective multicenter study (n=781).
Vendor-neutral deep learning reconstruction (SwiftMR) shortened T2-weighted liver MRI by ~9s, improved sharpness and SNR (p<0.001), but motion artifacts increased; single breath-hold reduced spatial mismatch in 86 patients.
Meta-analysis: AI radiomics models predict PD-L1 expression in NSCLC with AUC 0.78 (TPS≥1%) and 0.80 (TPS≥50%); ML better at TPS50, DL at TPS1.
Review of 91 models (2020-2026) for lung cancer screening selection or nodule classification showed AUCs ranging from ~0.70 to >0.90, but fewer than half were externally validated and calibration was inconsistently reported, highlighting that most models are not yet ready for cl…
In a multicenter retrospective study of 875 brain metastasis patients, a multimodal MRI-radiomics deep learning model predicted 1-year survival with AUCs up to 0.870 (training) and 0.740-0.788 (external validation), but C-indices were moderate (0.649-0.655), indicating limited d…
Integrating Mendelian randomization and placental single-cell data, researchers identified AKT1, CLEC7A, and CTSS as plasticizer-responsive genes associated with gestational diabetes. DEHP exposure altered CLEC7A in trophoblast cells, supporting a toxicogenomic hypothesis. Causa…
Novel indolylchalcone-benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase IX (Ki=8.9 nM) and XII (Ki=4.9 nM) with high selectivity over cytosolic isoforms, suggesting potential as anticancer leads (in vitro study).
In an RCT of 22 patients, computer-guided ridge split and expansion for narrow maxillae drastically improved implant accuracy: angular deviation 1.45° vs 10.02° freehand (p<0.001). Guided group also had significantly less marginal bone loss over 2 years. Preliminary, single-oper…
Patients who developed postop delirium after valve surgery had reduced preoperative ReHo in left hippocampus, precuneus, and rolandic operculum. An SVM model using these features and age discriminated cases (n=35, 7 events, prospective).
456 experts agreed foundational hepatology training must prioritize liver test interpretation and non-invasive fibrosis assessment (DI=0). Strong endorsement for procedural skills: paracentesis, elastography, variceal screening/endoscopic therapy. 79.1% support formal research m…
Incomplete Circle of Willis (CoW) predicted impaired long-term hemodynamics after STA-MCA bypass in Moyamoya disease: bridge artery flow decreased at late follow-up (P=0.02) while pulsatility index increased (P=0.03), suggesting higher vascular resistance. Preoperative CoW gradi…
In distal M2 thrombectomy, a sagittal tortuosity index ≥1.19 on baseline CTA was associated with a lower complete recanalization rate (mTICI 3: 39% vs 70%), fewer first-pass effects (11% vs 39%), and reduced 90-day functional independence (adjusted OR 0.11; 95%CI 0.02–0.53). Ext…
In a retrospective 46-patient study, endovascular embolization for left varicocele achieved 100% technical success, 97.8% clinical success, and only 2.2% recurrence. Outcomes similar across complex anatomies and coil+glue vs coil+polidocanol strategies, though the low event rate…
In a single-center study of 66 patients with biliary colic, single-session complete gallstone removal via percutaneous cholangioscopy (GO-SCOPE) was technically successful in 90.9%. At 3 months, 98.3% reported symptom improvement. A non-surgical alternative for those eligible fo…
An AI machine-learning model identified rosmarinic acid as a novel ALOX15 inhibitor. In a mouse model of colitis, it reduced disease activity, histological damage, and barrier protein loss by suppressing ferroptosis through the ALOX15-VDAC1 axis.
In amyloid-positive individuals, higher white matter injury marker PSMD conferred increased risk of clinical progression, adding independent prognostic value beyond amyloid status (two-cohort study).
A research article reports that implementing AI algorithms in radiology departments can enhance efficiency and generate financial returns (exact metrics not provided).
In a retrospective study of 716 patients, a multi-regional CT radiomics model combining primary and nodal features predicted 5-year recurrence in HPV+ oropharyngeal cancer with AUCs of 0.907 (training), 0.852 (internal validation), and 0.835 (external test), outperforming single…
In severe AS patients undergoing TAVR/SAVR, CT-FFR ≤0.80 tripled composite endpoint risk (HR 3.83, 95% CI 2.04–7.20) and quadrupled MACE risk (HR 4.84). CT-FFR improved reclassification (NRI 0.346) over clinical+CCTA models, while CCTA alone added little. Retrospective, single-c…
First-year medical students using HoloAnatomy mixed-reality in a non-cadaveric curriculum found it valuable for 3D visualization, spatial orientation, and collaborative review, but reported technical instability, physical discomfort, and limited realism; they viewed it as a usef…