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Automated CT erector spinae myosteatosis index correlates with handgrip strength in older surgical patients

Frontiers in medicineOct 7

Fully automated CT-based erector spinae muscle fat infiltration (IMAT Index) was associated with lower handgrip strength (ρ=-0.434, p=0.004) in 53 older surgical patients, but was not independently associated with global frailty after adjustment.

  • Retrospective cross-sectional study of 53 geriatric surgical patients (mean age 77.4 ± 4.4) using a fully automated DLM for muscle segmentation at L3.
  • Primary: erector spinae IMAT Index significantly correlated with handgrip strength (ρ=-0.434, p=0.004) and remained independent after adjustment (B=-1.808, 95% CI -2.994 to -0.622, p=0.004).
  • Small sample size, cross-sectional design, and incomplete functional testing (effective n=21-53 per model) limit generalizability; no independent association with Clinical Frailty Scale.

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