QSM Yields Superior Lateral Contrast for Centromedian Nucleus vs WMn and MP2RAGE

QSM shows greater lateral centromedian nucleus contrast than WMn and MP2RAGE, achieving a median CNR of 2.9 for medial pulvinar and 1.6 for ventral lateral thalamus, but lower SNR.

• QSM delineated the lateral CM border, achieving a median CNR of 2.9 (IQR 1.6–4.7) for medial pulvinar and 1.6 (0.6–2.3) for ventral lateral thalamus, outperforming WMn and MP2RAGE in lateral contrast.
• The comparison was indirect across separate retrospective cohorts (QSM n=24, WMn n=16, MP2RAGE n=24), limiting direct head-to-head conclusions.

Automated summary

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