SCOUT-Echo-AI Trial to Assess AI Liver Screening on Routine Echocardiography

A prospective multicenter trial (SCOUT-Echo-AI) will assess AI-based liver disease screening using routine echocardiography in ~3,000 patients, with primary outcomes of steatotic liver disease detection rate and positive predictive value within 12 months.

• Single-arm pragmatic interventional trial across multiple U.S. healthcare systems.
• EchoNet-Liver AI algorithm will analyze subcostal liver views from ~3,000 routine echocardiograms.
• Primary outcomes: detection rate and positive predictive value for steatotic liver disease and fibrosis within 12 months.

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