Phyllodes Tumor Update: Imaging Overlap with Fibroadenomas, Margin-Driven Prognosis, and Emerging AI Tools

Phyllodes tumors of the breast show significant imaging overlap with fibroadenomas. Core needle biopsy is key but limited by tumor heterogeneity. Surgical excision with negative margins remains the mainstay; local recurrence risk hinges on histologic grade and margin status. Eme…

• Mammography, ultrasound, and MRI contribute to preoperative assessment, but significant overlap with fibroadenomas persists, limiting specificity.
• Core needle biopsy is central to diagnosis, yet lesion heterogeneity can reduce the accuracy of histological grading.
• Emerging technologies such as artificial intelligence, radiomics, and digital pathology show promise in improving diagnostic accuracy and prognostic assessment.

Automated summary

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