Subcortical MRI radiomics and blood kynurenic acid nomogram identifies prior suicide attempts in depressed patients

In 164 depressed patients, a nomogram combining T1 MRI radiomics of subcortical structures and blood kynurenic acid distinguished those with vs without suicide attempts (C-index 0.919).

• Radiomic model using multiple subcortical regions alone had an AUC of 0.821 in the test cohort, improving on single-region models (right caudate AUC 0.793).

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