Chinese Expert Consensus on Lung Biopsy in ILD: 15 Evidence-Based Recommendations

New Chinese consensus on lung biopsy in ILD: 15 recommendations, mandatory MDD, HRCT-based stratification. Biopsy for uncertain diagnosis, not for definite UIP. TBLC preferred for fibrotic ILD; TBLB for granulomatous. Risk of AE-ILD higher with UIP pattern, active disease, low D…

• Contraindications: acute respiratory failure, severe pulmonary hypertension, hemodynamic instability, coagulopathy, end-stage debilitation. (Level of evidence: 1, strong)
• Site selection: target active lesions on HRCT, include interface of diseased/normal parenchyma, multi-lobar sampling from ≥2 sites of varying severity. (Level of evidence: 4, strong)
• Post-biopsy MDD integrates histopathology with clinical and imaging for final diagnosis; use international standardized nomenclature for pathology reports. (Level of evidence: 4, strong)

Evidence grade: Level of evidence 1-4, strong/conditional

Automated summary

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