Intra-arterial Bevacizumab for Chronic Subdural Hematoma: 35 Hemisphere Case Series

In 25 patients (35 hemispheres) with chronic subdural hematoma, intra-arterial bevacizumab into the middle meningeal artery led to >50% hematoma resolution in 80% of hemispheres and complete resolution in 25.7% at 90 days, with no rescue surgeries or neurological deterioration.

• 25 patients (median age 77) with asymptomatic or mild symptoms and mixed-density/membranous CSDH were treated.
• By 90 days, no rescue interventions, stroke, neurological deterioration, or mortality occurred.
• This suggests a novel endovascular approach, though it is a small, uncontrolled series.

Automated summary

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