Persistent subsolid nodules in children and adolescents: 10.5% show growth over median 34 months

Among 333 persistent subsolid nodules (SSNs) in 241 children and adolescents, 10.5% (35/333) showed interval growth over median 34 months follow-up. Part-solid nodules (PSNs) predicted growth. 95% of 21 resected nodules were early-stage adenocarcinoma. No deaths or metastases.

• PSNs independently predicted growth, and both PSN morphology and size ≥10 mm independently predicted subsequent lung cancer diagnosis.
• Authors recommend long-interval (≥2-year) follow-up for pure ground-glass nodules and short-interval (annual or shorter) follow-up for PSNs.

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.