Soft Tissue-RADS validated by fellowship-trained MSK radiologists in preliminary study

Soft Tissue-RADS accuracy for distinguishing benign from suspicious soft-tissue tumors on MRI was 82% vs 61% for qualitative reads (p<0.001), with good inter-reader agreement (κ=0.79) in a 150-patient validation by expert MSK radiologists.

• True positive rate for RADS category 6 (definite malignancy) was 97%.
• Reader AUCs 0.85–0.91; confidence higher with RADS versus qualitative assessment (4.35 vs 4.14, p<0.001).
• Limitation: Expert readers under curated conditions; further validation in routine clinical workflows is necessary.

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