Body / AbdominalAI / InformaticsResearch
CT Radiomics Predicts Tertiary Lymphoid Structures in Resectable HCC
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology1w ago
Preoperative CT radiomics ensemble model predicts tertiary lymphoid structures (TLS) in resectable HCC with AUC 0.842 in external validation (vs 0.732 for clinical model). TLS/MVI phenotypes linked to disease-free survival.
- The stacking ensemble (ITH-Ensemble) combined CT radiomics features, an intratumoral heterogeneity score, and clinicoradiological variables.
- TLS/MVI phenotypes showed distinct disease-free survival (log-rank p<0.0001): TLS+/MVI- had the best outcome, TLS-/MVI+ the worst.
- MVI status required pathology; a fully preoperative dual-factor framework would need independent imaging-based MVI prediction.
Evidence grade: 3
Automated summary
RadPigeon summaries are original and for information only. They are not clinical advice.