Semi-automated quantification of cerebral venous outflow on CTA aligns with visual scores in acute stroke

In 242 acute stroke patients, semi-automated quantitative cerebral venous attenuation on routine CTA correlated strongly with visual outflow scores (cortical ρ=0.72–0.77, AUC 0.81–0.95) and captured additional information beyond ordinal grading.

• Deep venous correlations were moderate but improved substantially in proximal occlusions.
• Results were consistent across centers and robust to arterial normalization.
• The method provides a scalable imaging biomarker directly applicable to routine stroke CT workflows.

Automated summary

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