HRCT in CTD-ILD: Advances in diagnosis and prognosis

For CTD-ILD, HRCT assessment still relies on conventional visual/semiquantitative scoring; quantitative CT and AI are emerging complementary tools. Most evidence in systemic sclerosis, RA, inflammatory myopathy. Validation needed.

• Conventional visual interpretation and semiquantitative scoring remain the clinical foundation for HRCT in CTD-ILD.
• Quantitative CT, radiomics, and AI are emerging complementary tools, but require standardization and prospective validation before broad implementation.
• Stronger evidence exists for systemic sclerosis, rheumatoid arthritis, and inflammatory myopathy-associated ILD; data for Sjögren syndrome and lupus are limited.

Automated summary

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