Quantitative imaging in hypertrophic cardiomyopathy: differentiating phenocopies and predicting prognosis

Quantitative imaging in HCM can extract texture, shape, and signal features beyond visual assessment to differentiate phenocopies, detect fibrosis without contrast, and predict sudden cardiac death and heart failure, but needs prospective validation.

• Radiomics extracts features of myocardial texture, shape, and signal heterogeneity beyond conventional visual assessment.
• It can help differentiate HCM from hypertensive heart disease and cardiac amyloidosis, detect fibrosis without contrast, and improve risk prediction for sudden cardiac death and heart failure.
• Most evidence comes from cardiac MRI, with smaller studies in echocardiography and CT; clinical adoption requires standardization and external validation.

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.