Multiparametric MRI radiomics stratifies incidental meningioma growth risk on external validation

A multiparametric MRI radiomics model predicted growth of incidental asymptomatic meningiomas with C-index 0.813 on external validation, beating clinical-only features by up to 0.223; a 9-point score cutoff of 5 stratified high- vs low-risk.

• Retrospective development/validation cohort included 519 patients from one institution (416 training, 103 internal validation) and 83 patients from two external institutions.
• Primary discrimination: random survival forest C-index 0.901 training, 0.837 internal validation, 0.813 external validation; significantly outperformed a clinical-only model (ΔC-index up to 0.223).
• A simplified 9-point radiomics score (cutoff = 5 points) stratified patients into high- and low-risk groups; prospective validation is required before clinical implementation.

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.