Ultrasound-guided steroid injections improve function, symptoms, and safety in carpal tunnel syndrome: overview of seven meta-analyses

Among 7 overlapping meta-analyses (AMSTAR 7–10), the highest-quality evidence favored ultrasound-guided corticosteroid injections for carpal tunnel syndrome: better Boston Carpal Tunnel Questionnaire function/symptom scores and fewer adverse events vs landmark-guided; grip stren…

• Seven overlapping meta-analyses of randomized controlled trials were appraised; AMSTAR scores ranged from 7 to 10 (median 8), and all included meta-analyses were categorized as Level-II evidence.
• The Jadad decision algorithm-selected meta-analysis found ultrasound guidance significantly improved Boston Carpal Tunnel Questionnaire functional status and symptom severity and lowered adverse event rates compared with landmark-guided injection.
• No significant differences were found for overall grip strength or electrophysiological measures, including compound muscle action potential, sensory nerve action potential, distal motor latency, and distal sensory latency.

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