Reference MRI prostate volume, PSA, and PSAD values in 1037 healthy German men

PSAD remained below 0.11 ng/mL² across all ages in 1037 healthy German men, contrasting with continuously rising PSA. 95th percentile reference: PV 51.39 mL, PSA 2.79 ng/mL, PSAD 0.071 ng/mL².

• Median PV was 31.29 mL, PSA 0.81 ng/mL, and PSAD 0.025 ng/mL².
• PSAD was age-stable, peaking at 71 years and declining thereafter, while PV and PSA increased continuously.
• An open-access calculator provides personalized age- and BMI-adjusted percentiles for clinical use.

Automated summary

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