UFE vs myomectomy subtypes: 30-day safety in 59,484 women

Uterine fibroid embolization (UFE) had 2.5% 30-day major adverse events vs 5.4% for abdominal myomectomy (odds ratio 0.44), but 1.95x higher than hysteroscopic myomectomy (1.0%). Pooling subtypes obscures differences.

• Retrospective MarketScan claims analysis of 59,484 women aged 25-50 undergoing first fibroid procedure (2013-2025) with inverse probability weighting.
• 30-day readmission was significantly lower for UFE vs abdominal myomectomy (OR 0.19) but higher vs hysteroscopic (OR 2.50).
• Emergency department visits were more frequent after UFE than after any myomectomy subtype (OR 1.30-2.38).

Automated summary

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