AJR Expert Panel Review on Whole-Body MRI Screening: Promises and Perils

WB-MRI for asymptomatic screening is growing commercially despite limited evidence, no guideline endorsement, and potential harms—overdiagnosis, false-positive workup, high costs. AJR expert panel calls for prospective trials, targeted screening, and quality standards.

• Nononcologic applications include intracranial aneurysm detection, body composition, and musculoskeletal assessment.
• Standardized acquisition/reporting frameworks and AI workflows are in development to support implementation.
• Ethical concerns include unregulated advertising, informed consent gaps, and psychosocial effects.

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