Expert Panel Backs Cautious AI Integration for ARIA Detection on MRI in Alzheimer Disease Therapy

AI-assisted detection of amyloid-related imaging abnormalities (ARIA) on MRI during anti-amyloid therapy should be used only as clinical decision support with a radiologist in the loop, an expert panel says, citing tool variability and need for outcome studies.

• Multidisciplinary panel concluded AI-assisted ARIA detection likely improves patient safety when used as decision support within a radiologist-in-the-loop framework.
• Substantial variability exists among commercially available tools in regulatory status, technical capabilities, and validation; prospective outcome studies are needed.
• Panel supported conditional implementation with radiologist oversight, ongoing quality assurance, and monitoring of clinical performance.

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