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AI-derived liver and adrenal volumes linked to survival in kidney cancer

Annals of medicine2d ago

Higher CT-derived liver volume (HR 1.42) and right adrenal gland volume (HR 1.34) were independently associated with worse overall survival in clear cell renal cell carcinoma patients; no association with recurrence-free survival after adjustment.

  • Compared with healthy controls, ccRCC patients had higher spleen and adrenal gland volume indices and lower pancreatic volume index.
  • No organ volume parameter was associated with recurrence-free survival after multiple-testing correction.
  • Findings require external validation and further mechanistic investigation.

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