MRI in ALS: Imaging Beyond the Brain and Spinal Cord

MRI of body fat and muscles can help understand and monitor amyotrophic lateral sclerosis (ALS), with multiparametric approaches and machine learning showing promise.

• Structures outside the CNS, such as body fat and muscles, are assessable by MRI and reflect core ALS pathology.
• Multiparametric MRI and machine learning could improve disease monitoring.

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