Attention U-Net using contrast-enhanced T1, T1, and FLAIR MRI achieves high meningioma detection and segmentation

In 149 patients, an Attention U-Net using contrast-enhanced T1-weighted, T1-weighted, and FLAIR MRI detected meningiomas with detection rate 0.98 (SD 0.03) and Dice 0.82 (SD 0.04), compared with contrast-enhanced T1 alone at 0.79 and Dice 0.67.

• Among single-sequence models, contrast-enhanced T1-weighted MRI performed best, with detection rate 0.79±0.11 and Dice 0.67±0.10.
• Models trained on multiple MRI sequences up to three consistently outperformed single-sequence models; T1-CE + T1 + FLAIR had the highest detection and segmentation performance.
• The study retrospectively analyzed 149 patients with histologically diagnosed meningioma, using manual segmentation by one experienced neuroradiologist as the reference standard.

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