Pediatric CNS Tuberculosis Shows More Meningovascular Complications on Imaging than Adults

In a meta-analysis, children with central nervous system tuberculosis had higher pooled imaging prevalence of leptomeningeal enhancement (89% vs 61%), hydrocephalus (81% vs 36%), and infarcts (65% vs 33%) than adults.

• Tuberculomas showed similar prevalence (approximately 60%) in both age groups, mostly multiple.
• Advanced MRI (DWI, MRS, vessel wall imaging) provided detailed lesion characterization.
• Spinal involvement was studied almost exclusively in adults, limiting pediatric comparison.

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