CT-derived fractional flow reserve accurately detects significant CAD in TAVI patients

CT-derived FFR (CT-FFR) showed good diagnostic performance for hemodynamically significant coronary artery disease in 37 TAVI candidates with severe aortic stenosis; no 30-day deaths, MIs, or strokes occurred.

• Single-centre retrospective study of 37 severe AS patients undergoing TAVI.
• CT-FFR was analyzed with deep learning software (threshold ≤0.05) and compared to invasive angiography.
• Authors conclude CT-FFR provides good diagnostic performance, but larger prospective studies are needed to validate findings.

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