Automated segmentation and bone-length measurement in pediatric hand radiographs

An automated tool (Auto-Bone-Caliper) segmented all 19 metacarpal and phalangeal bones in pediatric hand radiographs with Dice scores of 98.7% (normal) and 95.0% (dysmorphic); length errors were 2.2% and 4.5%.

• On an independent dataset, relative bone-length measures agreed closely with a healthy reference catalog (Wasserstein-1 distance 0.012).
• Relative metacarpophalangeal pattern profiles were demonstrated for Turner syndrome, achondroplasia, and pseudohypoparathyroidism.
• Auto-Bone-Caliper integrates InstanceSAM segmentation with k-means-based length estimation to enable scale-independent relative measurements.

Automated summary

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