AI Enables Opportunistic Quantification of Bone Mineral Density and Microarchitecture

AI enables opportunistic BMD assessment from radiography, CT, and MRI; CT deep learning yields correlations of 0.8-0.9 versus reference quantitative CT. Barriers: interoperability, reimbursement, model explainability.

• CT-based AI pipelines achieve correlations of 0.8-0.9 versus reference techniques and near-perfect agreement with dedicated quantitative CT.
• Radiography-based AI approaches near-DXA precision by integrating texture and clinical features.
• Key barriers to translation include interoperability, lack of reimbursement, and limited model explainability.

Automated summary

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