MRI radiomics predicts pituitary adenoma consistency, subtype, and recurrence

MRI radiomics predicts pituitary adenoma consistency, molecular subtype, and recurrence often with AUCs >0.80, but clinical translation awaits multicenter validation.

• Radiomics from T2-weighted and multiparametric MRI differentiates functional vs non-functional adenomas, granulation patterns, and silent corticotroph tumors.
• Features predict Ki-67 expression, cavernous sinus invasion, and treatment response, including to dopamine agonists.
• Most studies are single-center and retrospective, lacking external validation and adherence to reporting guidelines.

Automated summary

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