Ferumoxytol Improves Vascular Suppression and Nerve Conspicuity on Brachial Plexus MR Neurography

In brachial plexus MR neurography, ferumoxytol improved vascular suppression vs both noncontrast (P<.001) and gadolinium-enhanced scans (P=.04), and improved conspicuity of suprascapular, axillary, and long thoracic nerves vs noncontrast.

• Prospective study in 18 participants; ferumoxytol improved vascular suppression (P<.001 vs noncontrast, P=.04 vs gadolinium).
• Rater 2 observed improved conspicuity of suprascapular (P=.01), axillary (P=.02), and long thoracic nerves (P=.004) vs noncontrast; rater 1 showed trends but not significant (P≥.06).
• No significant difference in nerve conspicuity between ferumoxytol and gadolinium (P≥.17) and no discrepancy in abnormal nerve detection (all P≥.48).

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