Body / AbdominalAI / InformaticsResearch

Multicenter DCE-CT nomogram predicts VETC in hepatocellular carcinoma

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology1w ago

A DCE-CT nomogram integrating intratumoral heterogeneity and body fat predicted vessels encapsulating tumor clusters (VETC) in hepatocellular carcinoma with AUC 0.847 (internal) and 0.814 (external) in 360 patients; higher scores also linked to shorter recurrence-free survival.

  • Independent predictors included intratumor necrosis, non-smooth tumor margin, total adipose tissue index, and portal venous phase ITH Score.
  • Nomogram assistance improved diagnostic accuracy, particularly for the junior radiologist.
  • VETC-negative patients had significantly longer recurrence-free survival (P < 0.0001), and higher nomogram scores correlated with shorter recurrence-free survival (log-rank P < 0.05).
Read the source

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.