CT radiomics predicts pathologic response after neoadjuvant chemoimmunotherapy in stage III NSCLC

A preoperative CT radiomics model predicted pathological complete response in 29 stage III NSCLC patients after chemoimmunotherapy with AUC 0.92 (95% CI 0.81-1.00), 90% sensitivity, and 92% specificity.

• In this retrospective study, 9 of 29 patients (31%) achieved pathologic complete response.
• All patients classified as complete responders by the model were confirmed at histology.

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