Maximizing Diagnostic Yield of Gadolinium-Enhanced CNS MRI

Maximizing diagnostic yield of CNS MRI with gadolinium requires optimized dosing, timing, and sequence selection; high-relaxivity agents allow dose reduction without loss of accuracy, and AI may further improve low-dose imaging.

• Common pitfalls include incorrect dosing, inadequate timing, and suboptimal sequence parameters.
• High-relaxivity macrocyclic agents enable dose reduction without sacrificing diagnostic accuracy.
• Advanced techniques (perfusion, Dixon, black-blood, SWI) and emerging AI can enhance contrast utilization and diagnostic precision.

Automated summary

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