High-Confidence mpMRI May Allow Men to Skip Prostate Biopsy

In 880 men, mpMRI readings with 99% certainty of prostate cancer had 100% clinically significant tumors on biopsy. At 90% certainty, 98% had significant disease. Overall, 14% of patients could potentially skip biopsy and proceed directly to treatment.

• 79 patients (9% of total) were in the 99% certainty group; 69 underwent biopsy and all had clinically significant tumors.
• 45 patients (5%) were in the 90% certainty group; 41 biopsied, 98% had clinically significant tumors.
• Combined groups represented 14% of all patients and 49% of suspicious cases. Only one patient lacked a clinically significant tumor.

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