MRI radiomics predicts conservative-management eligibility in early endometrial cancer

MRI radiomics predicted eligibility for conservative management in early endometrial cancer: an MLP model had an internal validation AUC of 0.946 (95% CI 0.915–0.973) and external test AUC 0.792 (95% CI 0.571–0.965).

• Retrospective study of 184 patients from two centers: training set 123, internal validation 31, external test 30.
• Radiomics features were extracted from T2-weighted, dynamic contrast-enhanced T1-weighted, and apparent diffusion coefficient maps.
• Decision curve analysis showed high net benefit for the MLP model at threshold probabilities from 0.1 to 0.9.

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