Body / AbdominalResearch

40-keV Virtual Monoenergetic Photon-Counting CT Improves Muscle Invasion Staging in Bladder Cancer

AJR. American journal of roentgenologyyesterday

In 110 patients, photon-counting CT 40-keV VMIs increased accuracy for muscle invasion vs conventional polychromatic images (reader 1: 86.4% vs 66.4%) and specificity (83.1% vs 56.6%), with similar sensitivity (96.3% for both).

  • 40 keV was the optimal VMI, yielding highest tumor SNR, CNR, and subjective conspicuity.
  • For all three readers, accuracy and specificity were significantly higher with 40-keV VMIs (p .99), while sensitivity was similar.

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