Deep-learning contrast boosting improves lesion conspicuity on standard-dose brain MRI

AI post-processing of standard-dose contrast-enhanced brain MRI improved lesion conspicuity: contrast-to-noise ratio up 495.16%, lesion-to-brain ratio up 58.94%, contrast enhancement up 160.55%; readers preferred it in up to 84.9% of cases.

• Retrospective, multicenter, multireader study of 86 adults with standard-dose contrast-enhanced brain MRI; three neuroradiologists evaluated AiMIFY-processed versus standard post-contrast images.
• Quantitative increases with AiMIFY: CNR 495.16% (p<0.001), LBR 58.94% (p<0.001), CEP 160.55% (p<0.001); subjective scores improved for border delineation, internal morphology, and contrast enhancement (all p<0.05).
• Small lesions (<10 mm) showed higher subjective scores with AiMIFY; readers preferred AiMIFY-processed images in 84.9%, 29.1%, and 68.6% of cases (all p<0.001).

Automated summary

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