Spontaneous Contractions Lower Placental T2* by 4.64 ms, Hyperoxia Raises It by 11.36 ms

In 46 pregnant participants, spontaneous non-labor uterine contractions reduced placental T2* by 4.64±0.75 ms, while maternal hyperoxia increased it by 11.36±0.62 ms. Contraction-induced T2* reduction and deformation intensified with gestational age and duration.

• During normoxia, complete contractions reduced placental T2* by 4.64±0.75 ms, while hyperoxia increased it by 11.36±0.62 ms relative to normoxia.
• Contractions reduced the T2* difference between cotyledons and surrounding tissue (β=3.14±1.34 ms), whereas hyperoxia preserved regional heterogeneity (p=0.48).
• Study design was retrospective.

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