Expiratory CT Plus Lobar Analysis Improves Detection of Chronic Airflow Limitation

Adding expiratory CT and lobar analysis improved AUC for chronic airflow limitation detection from 0.66 (inspiratory alone) to 0.81, with 79% sensitivity and 94% NPV.

• Expiratory CT alone had stronger discrimination than inspiratory CT (AUC 0.77 vs 0.66).
• Lobar analysis added modest further improvement (AUC 0.81) and provided regional information.

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