MRI radiomics with 5-mm perilesional expansion best diagnoses chronic osteomyelitis

In 102 patients with suspected chronic osteomyelitis, MRI radiomics using logistic regression and a 5-mm perilesional ROI expansion achieved the highest diagnostic AUC, with significant differences versus 0-mm and 10-mm expansions (DeLong p<0.05). The 10-mm model better detected…

• Logistic regression outperformed KNN, SVM, and random forest algorithms across all ROI expansion ranges.
• The 5-mm expansion model yielded superior diagnostic performance, supporting moderate perilesional debridement.
• The 10-mm expansion model showed advantages in detecting more extensive tissue alterations, aiding comprehensive lesion assessment.

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