Automated CT Volumetry of Peripancreatic Collections Outperforms mCTSI for Risk Stratification in Acute Pancreatitis

Automated CT volumetry of peripancreatic collections predicts organ failure (AUC 0.82 vs mCTSI 0.73) and infection (AUC 0.79 vs 0.72) in acute pancreatitis, 25.2s vs 12.4min per patient.

• Automated segmentation showed excellent agreement with manual reference (Dice coefficient 0.89; 95% CI 0.87-0.90) in the external test cohort.
• Automated peripancreatic collection volume (per 100 mL) was independently associated with organ failure and infection (all P ≤ 0.006).
• The tool was significantly faster than manual segmentation (median 25.2 seconds vs. 12.4 minutes) and surpassed radiologists' subjective binary classification.

Automated summary

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