Multi-View AI Model Detects LVOT Obstruction in HCM Without Doppler, AUC 0.84 on External Validation

AI model using multi-view 2D echo (no Doppler) classified LVOT obstruction (>20 mm Hg) in hypertrophic cardiomyopathy with external validation AUC 0.84. Enables scalable, cost-effective screening.

• EchoPrime foundational model achieved single-view external AUCs of 0.79–0.83; multi-view fusion improved performance to AUC 0.84.
• The approach leverages routine 2D echocardiographic windows without Doppler, offering potential for portable or resource-limited settings and substantial cost savings compared with screen-all.

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