Chest X-ray biological age predicts mortality after structural heart interventions beyond EuroSCORE II

Chest X-ray biological age predicts 30-day mortality after TAVI (AUC 0.952 vs 0.745 for EuroSCORE II) and surgical procedures, with 10-year excess biological age linked to higher complications (17.3% vs 9.2%).

• In surgical (non-TAVI) patients, biological age AUC for 30-day mortality was 0.874 vs 0.785 for EuroSCORE II (P<0.001), though STS-PROM had AUC 0.949.
• After adjustment, each additional year of biological age independently predicted 30-day mortality in TAVI patients (OR 1.58, 95% CI 1.27–2.12).

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