Neuro / Head & NeckMusculoskeletal (MSK)AI / InformaticsResearch

Explainable Random Forest Predicts Adjacent Segment Degeneration After Lumbar Fusion

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An externally validated random forest model predicted radiographic adjacent segment degeneration after short-segment lumbar fusion (AUROC 0.782 internal test, 0.749 external). Five perioperative variables were integrated; preoperative intervertebral space height was the stronges…

  • Model integrates preoperative intervertebral space height, postoperative PI-LL mismatch, frailty, Coflex implantation, and WOMAC lower-extremity dysfunction.
  • Among logistic regression, random forest, XGBoost, LightGBM, and multilayer perceptron, random forest achieved the highest discrimination.

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