Musculoskeletal (MSK)AI / InformaticsResearch

Manus AI with CBCT Achieves 95% Detection and Diagnosis of Jaw Lesions, Outperforming Other Chatbots

Dento maxillo facial radiologytoday

Manus AI using cone beam CT (CBCT) data achieved 95% detection and correct diagnosis of jaw lesions in 97 patients. Gemini 2.5 Pro detected 80% but correctly diagnosed 56%. Copilot and Claude were least accurate. Significant differences between chatbots.

  • In 97 patients with jaw lesions, Manus chatbot reading raw CBCT data detected and correctly diagnosed 95% of lesions, while the same bot using panoramic images was less accurate.
  • Gemini 2.5 Pro using panoramic images detected 80% of lesions but gave a correct diagnosis in only 56%, indicating many false positives or misdiagnoses.
  • Integration of raw 3D CBCT data substantially improved performance, suggesting that diagnostic chatbots benefit from advanced imaging data over 2D views.

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