Cardiac MRI reveals diffuse myocardial injury beyond the infarct zone in multivessel disease after acute MI

After acute MI, multivessel disease (MVD) shows higher native T1, extracellular volume, and T2 in remote myocardium vs. single-vessel disease, differences persisting after adjusting for infarct size. Incomplete revascularization links to elevated remote ECV and T2.

• Primary result: After adjustment for age, diabetes, hyperlipidemia, BMI, and infarct size, MVD had significantly higher native T1 (p=0.041), extracellular volume (p<0.001), and T2 (p<0.001) in the remote zone compared with single-vessel disease.
• Secondary finding: Among MVD patients, incomplete revascularization was associated with higher extracellular volume in the peri-infarct zone (p=0.023), extracellular volume in the remote zone (p=0.025), and T2 in the remote zone (p=0.003).

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.