Multiorgan thrombosis pattern points to antiphospholipid syndrome

Budd-Chiari, splenomegaly, and bilateral adrenal infarction on imaging should prompt consideration of a unifying hypercoagulable disorder such as antiphospholipid syndrome.

• Budd-Chiari syndrome results from hepatic venous outflow obstruction, leading to portal hypertension and splenomegaly.
• Bilateral adrenal infarction is caused by adrenal vein thrombosis, a hallmark of hypercoagulable states.
• When these findings coexist, suspect an underlying disorder like antiphospholipid syndrome rather than isolated organ pathology.

Automated summary

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