Automated 3D fetal brain volumes show strong correlation with clinical 2D linear measurements

In 70 clinical fetal MRIs, automated slice-to-volume reconstruction with brain segmentation took 8.6 minutes and was rated "good" in 70% of cases. Derived supratentorial, cerebellar, and brainstem volumes strongly correlated with traditional 2D linear measurements (r=0.88–0.94),…

• In 70 patients (28.2 ± 4.3 weeks gestational age), automated reconstruction plus volumetric analysis required 8.6 ± 3.4 minutes; processing time positively correlated with gestational age (r=0.78).
• Automated segmentation quality was rated good in 70% (49/70) and poor in 17.1% (12/70) of cases; fetuses with poor-quality segmentation had significantly lower mean gestational age (25.1 vs. 28.9 weeks, p=0.004).
• This single-center, retrospective study evaluated a vendor-specific (Philips PRIDE) research pipeline without external or prospective validation.

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