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Imaging's Role in Screening for Fibrosis in MASLD

AJR. American journal of roentgenologytoday

MASLD affects 40% of the global population. Professional guidelines recommend screening high-risk adults with blood tests first, then noninvasive imaging to detect clinically significant fibrosis and guide management.

  • Clinically significant fibrosis (stage F2 or higher) in MASLD is associated with poorer prognosis and guides management decisions, including pharmacotherapy and surveillance.
  • Screening targets high-risk adults with diabetes, other cardiometabolic factors, or incidentally detected steatosis.
  • Imaging serves as a second-line test to verify and stratify fibrosis risk after initial blood-based tests.

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