BreastResearch

CEM Specificity Improves in Incidence Screening Rounds for High-Risk Women

Radiology4w ago

In women at high breast cancer risk, CEM incidence screens had higher specificity (91.5% vs 83.4%) and accuracy (91.4% vs 83.5%) than prevalence screens, with similar cancer detection rates (11.6 vs 19 per 1000).

  • No significant difference in cancer detection rate (19 vs 11.6 per 1000, P=.65) or incremental CDR (11.4 vs 6.7 per 1000, P=.10) between prevalence and incidence screens.
  • Incidence CEM specificity: 91.5% (83.4% for prevalence; P=.008); accuracy: 91.4% (vs 83.5%; P=.01).
  • Contrast enhancement alone accounted for 58–60% of cancers detected.

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