Neuro / Head & NeckEmergencyAI / InformaticsResearch
Denoising autoencoder recovers CT perfusion image quality at 90% simulated dose reduction
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)yesterday
A denoising autoencoder restored CT perfusion image quality at up to 90% simulated radiation dose reduction (SSIM 0.81, PSNR 43 dB) and reduced infarct core volume error from 10-30 mL to 4-16 mL, with high agreement (R²>0.85).
- 48 acute ischemic stroke patients from the PRove-IT trial; low-dose simulated by adding noise in sinogram and image domains.
- At 90% dose reduction, DAE restored source image SSIM to 0.81 and PSNR to 43 dB.
- Denoising reduced mean absolute error of CBF-derived infarct core volumes from 10-30 mL to 4-16 mL, with R²>0.85.
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